See all Zoo in Knoxville Knoxville for: Adventure, Food And Dining, Art And Culture, Nightlife, Spa, History, First Timers, Family, Romance, Shopping Knoxville Zoo About Knoxville Zoo is a 53-acre (21 ha) zoo located just east of downtown Knoxville, Tennessee near exit 392 of Interstate 40. The zoo is home to about 800 animals and welcomes over 400,000 human visitors each year. Add to Wish List
